Protein Details: Potassium channel subfamily K member 15

Protein ID

ICDB_Pro_1308

Protein Name

Potassium channel subfamily K member 15

Gene Name

Kcnk15; Task5

Organism

Rattus norvegicus (Rat)

Length

318 amino acids

AlphaFoldDB

AF-Q8R5I0-F1-model_v4.pdb

Function

Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.

Sequence

MRKQSARTAALILCILSYLLVGAAVFDALESEAERSRQRLLARKRGEFRRKYRFSADDYRELERLALQAEPHRAGRQWRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNALVRCLLLAAKRCLGLRRPHVSAENMVVAGLLLCAATLALGAAAFAHFEGWTFFHAYYYCFITLTTIGFGDFVALQRDEALQKKPPYVAFSFLYILLGLTVIGAFLNLVVLRFLASAEAPERAALRRASVFRRGAPESRVRIPYPFHPLETWARDNPAFSPPLSPEAVHDCHSSPDRLRARRKSI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Brain-specific. Highly expressed in auditory nuclei; in Purkinje cells and in olfactory bulb mitral cells.

DOI ID

10.1006/mcne.2001.1045

RefSeq

NP_570826.1